Python_Anesthesia_Simulator

The Python Anesthesia Simulator (PAS) models the effect of drugs on physiological variables during total intravenous anesthesia. It is particularly dedicated to the control community, to be used as a benchmark for the design of multidrug controllers. The available drugs are Propofol, Remifentanil, and Norepinephrine, the outputs are the Bispectral index (BIS), Mean Arterial Pressure (MAP), Cardiac Output (CO), and Tolerance of Laryngoscopy (TOL). PAS includes different well-known models along with their uncertainties to simulate inter-patient variability. Blood loss can also be simulated to assess the controller's performance in a shock scenario. Finally, PAS includes standard disturbance profiles and metrics computation to facilitate the evaluation of the controller's performances.

• Documentation and examples: https://python-anesthesia-simulator-doc.readthedocs.io
• Associated paper: https://joss.theoj.org/papers/10.21105/joss.05480

Installation

Use pip to install the package:

    pip install python-anesthesia-simulator

Or, to get the latest version, clone this repository and install the package with:

    pip install .

Citation

To cite PAS in your work, cite this paper:

Aubouin-Pairault et al., (2023). PAS: a Python Anesthesia Simulator for drug control. Journal of Open Source Software, 8(88), 5480, https://doi.org/10.21105/joss.05480

Guidelines

Contribution and discussions are welcomed! Please feel free to use the issue tracker ensuring that you follow our contribution guide and our Code of Conduct.

Structure

.
├─── src
|   ├─── python_anesthesia_simulator           # Simulator library + metrics function
|
├── tests              # files for testing the package
|
├── docs               # files for generating the docs
| 
├── LICENSE
├── pyproject.toml      # packaging file
├── requirements.txt
├── README.md
└── .gitignore          

License

GNU General Public License 3.0

Project status

Published in the journal of Open Source Software!

Author

Bob Aubouin--Paitault