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@pirl-unc Personalized Immunotherapy Research Lab @ UNC

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    81 repositories

    • vstol

      Public
      Variant Standardization, Tabulation, and Operations Library
      Python
      •0•1•0•0•Updated Jul 28, 2025Jul 28, 2025

    • pirlygenes

      Public
      Gene sets used for cancer immunotherapy expression analysis
      Jupyter Notebook
      •
      Apache License 2.0
      •0•0•1•0•Updated May 27, 2025May 27, 2025

    • ace

      Public
      Jupyter Notebook
      •1•2•3•0•Updated May 13, 2025May 13, 2025

    • datasetprep

      Public
      Methods to make life easier when preparing datasets for analysis.
      R
      •
      Apache License 2.0
      •0•0•1•0•Updated May 5, 2025May 5, 2025

    • nexus

      Public
      Nextflow
      •1•1•0•0•Updated Apr 30, 2025Apr 30, 2025

    • lens_demo_workflow_outputs

      Public
      HTML
      •0•0•0•0•Updated Apr 30, 2025Apr 30, 2025

    • pdf-reports

      Public
      Helping code for compiling plots and other outputs into presentation pdfs.
      R
      •
      GNU General Public License v3.0
      •0•0•0•0•Updated Apr 11, 2025Apr 11, 2025

    • PRAME_in_NUT_Carcinoma

      Public
      R
      •
      MIT License
      •0•0•0•0•Updated Apr 2, 2025Apr 2, 2025

    • rserver-binfotron

      Public
      Dockerfile
      •
      Apache License 2.0
      •1•0•2•0•Updated Apr 1, 2025Apr 1, 2025

    • housekeeping

      Public
      R
      •
      Apache License 2.0
      •0•0•0•0•Updated Apr 1, 2025Apr 1, 2025

    • binfotron

      Public
      R
      •
      Apache License 2.0
      •1•1•3•0•Updated Apr 1, 2025Apr 1, 2025

    • translate-pacbio-reads-for-bbn963

      Public
      Jupyter Notebook
      •
      Apache License 2.0
      •0•0•0•0•Updated Mar 26, 2025Mar 26, 2025

    • longread-fusion-transcript-pipeline

      Public
      R
      •0•0•0•0•Updated Mar 24, 2025Mar 24, 2025

    • mhcgnomes

      Public
      Parsing MHC nomenclature in the wild
      Python
      •
      Apache License 2.0
      •3•17•11•0•Updated Mar 24, 2025Mar 24, 2025

    • lineardesign

      Public
      docker image to run externally developed LinearDesign software
      GNU General Public License v3.0
      •0•0•0•0•Updated Feb 28, 2025Feb 28, 2025

    • MiXCR

      Public
      Dockerfile and script to run MiXCR
      Dockerfile
      •
      Apache License 2.0
      •0•0•0•0•Updated Feb 25, 2025Feb 25, 2025

    • pvacitopes

      Public
      Epitope selection from pVACtools output
      Python
      •
      Apache License 2.0
      •0•0•0•0•Updated Feb 19, 2025Feb 19, 2025

    • tcr_translate

      Public
      Accompanying Repository to TCR-TRANSLATE paper.
      Python
      •
      Other
      •1•1•0•0•Updated Dec 19, 2024Dec 19, 2024

    • TCRpMHCdataset

      Public
      Python Class for Handling Many-to-Many Nature of TCR::pMHC Data
      Python
      •
      Apache License 2.0
      •1•1•0•0•Updated Dec 15, 2024Dec 15, 2024

    • NeoantigenProfiler

      Public
      R
      •0•0•0•0•Updated Dec 13, 2024Dec 13, 2024

    • bbn963_fusion_transcript_pipeline

      Public
      A pipeline associated with the longread fusion pipeline used to extract fusions from our associated pacbio bbn963 data.
      R
      •0•0•0•0•Updated Dec 13, 2024Dec 13, 2024

    • nutm1-fusions

      Public
      Hunting for T-cell epitopes in recurrent NUTM1 somatic fusions
      Jupyter Notebook
      •
      Apache License 2.0
      •0•0•0•0•Updated Dec 11, 2024Dec 11, 2024

    • lens

      Public
      Landscape of Effective Neoantigens Software
      0•0•0•0•Updated Nov 12, 2024Nov 12, 2024

    • weirdo

      Public
      Metrics of immunological foreignness for candidate T-cell epitopes
      Jupyter Notebook
      •
      Apache License 2.0
      •0•0•0•0•Updated Oct 7, 2024Oct 7, 2024

    • yolotrim

      Public
      Heuristic read trimming for PacBio IsoSeq data
      Rust
      •
      Apache License 2.0
      •0•0•0•0•Updated Oct 7, 2024Oct 7, 2024

    • tcrsift

      Public
      Python
      •
      Apache License 2.0
      •0•0•0•0•Updated Aug 10, 2024Aug 10, 2024

    • PostRNASeqAlign

      Public
      R
      •
      Apache License 2.0
      •0•0•0•0•Updated Jul 24, 2024Jul 24, 2024

    • nara

      Public
      NUTM1 Associated Recurrent Antigens: possible T-cell targets on NUTM1 rearranged neoplasms
      Jupyter Notebook
      •
      Apache License 2.0
      •0•0•0•0•Updated Jun 25, 2024Jun 25, 2024

    • rserver-immunesubtypes

      Public
      hosts dockerfile for running immune subtypes package
      Dockerfile
      •
      Apache License 2.0
      •0•0•0•0•Updated Jun 13, 2024Jun 13, 2024

    • variform

      Public
      Variant isoform detection for large mutations in long-read RNA sequencing
      Python
      •
      Apache License 2.0
      •0•1•0•0•Updated Apr 9, 2024Apr 9, 2024